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VOL 7 2026; ISSUE 2

Effect of Fumarate on Nuclear Factor Erythroid 2 and Transforming Growth Factorβ1 Signaling in Doxorubicin-Induced Cardiorenal Injury.

https://doi.org/10.61594/tnpr.v7i2.2026.158

Osaze Edosuyi, Owolabi Olusola Ajiboye, Zainab Olawunmi Lawal, Ayomide Peace Adeyeye, Ilekhuoba Osazee Eric, Ojeagbase Choice Ohiakhueche, Vashti Edosuyi, Edo-Izevbizua Osazee Emmanuel, Aladuna Joseph Omo-Erhabor, Ighodaro Igbe. 

 

Effects of Syzygium aromaticum (L.) Merr. & LM Perry (Cloves) Extract on Uterine Contractions and its Underlying Mechanisms: An Ex vivo Study
https://doi.org/10.61594/tnpr.v7i2.2026.159

Adaeze Phina Uchendu, Eghosasere Efe-Oghosa Eghianruwa

 

 

Aloe vera (Aloe barbadensis Miller) derived hydrocolloid; isolation, characterization and its application as a stabilizer in oil-in- water emulsions

https://doi.org/10.61594/tnpr.v7i2.2026.160

Frank Ohwoavworhua, Ademola Oduola, Mathias Iji, Gideon Okpanachi, Akila James, Alheri Samaila, Sahara Kwarams.

Green Synthesis of Hydroxyapatite Nanoparticles from Catfish Bone: A Novel Approach for Sustainable Biomaterial intended for Biomedical Applications.

https://doi.org/10.61594/tnpr.v7i2.2026.161

Frank Ohwoavworhua, Abishag Stephen, Ademola Oduola, Mamuda Bappah 

 

In Vitro and In Vivo Comparative Evaluation of Biological Activities in Freshly Homogenized and Oven-Dried Chrysophyllum albidum G. Don Fruits Extracts and Their Ethyl Acetate Fractions.

https://doi.org/10.61594/tnpr.v7i2.2026.162

Joshua Ayo Alabi, Olaitan Olabamiji Olabiyi, Abayomi Mayowa Ajayi

 

Effect of Essential Oil of Asparagus officinalis L on Haematological Parameters of Swiss Mice

https://doi.org/10.61594/tnpr.v7i2.2026.163

Samuel Dolapo Oyemitan, Ayokunmi Stephen Olusa, Idris Ajayi Oyemitan

 

Gongronema latifolium Benth methanol leaf extract reduces blood pressure in L-NAME-induced hypertension in rats via modulation of aortic endothelial nitric oxide
synthase

https://doi.org/10.61594/tnpr.v7i2.2026.164

Joseph Ayotunde Badejo, Gospel Udochukwu Okpara, Andrew Oluwapelumi. Eseola, Chinwenwa. Obiajulu Ezeofor, Obaro Stanley Michael, Mayowa Abayomi Ajayi, Ezekiel Olugbenga Iwalewa.

 

Preliminary evaluation of the antidiabetic and antioxidant potentials of a herbal formulation

https://doi.org/10.61594/tnpr.v7i2.2026.165

Joseph Oisemuzeimen Oiseoghaede, Fatima Yetunde Ayeola, Fatima Agbeke Agboke, 

 

 

Healing Effects of the Methanol Extracts of Vernonia amygdalina (Asteraceae) Ocimumgratissimum, (Lamiaceae) and their Combination on Croton Oil-Induced Hemorrhoid in Rats

https://doi.org/10.61594/tnpr.v7i2.2026.166

Mary Olufunmilayo Ologe, Olufunke Julianah Iwalewa, Joseph Ayotunde Badejo, Emmanuel Adegboyega Iwalewa, Ezekiel Olugbenga Iwalewa.

 

Pharmacotherapeutic effects of a Plant- derived Stem Cell (PDSC) in Fructose-fed Streptozotocin-induced diabetic Wistar rats

https://doi.org/10.61594/tnpr.v7i2.2026.167

Ifedolapo Adesola Adejumo, Muyiwa Samuel Fageyinbo, Sikiru Olatunji Usman, Okwara Onyebuchi Success, Uwawuike Nkechi Amanda, Olosunde Tolulope Oluwaseun, Ibrahim Adekunle Oreagba, Esther Oluwatoyin Agbaje

 

 

VOL 7 2026; ISSUE 1

Alchornea laxiflora [Benth.] Pax and K.Hoffm stem bark extract and fractions attenuated oxidative stress and liver injury in Plasmodium berghei-infected mice

https://doi.org/10.61594/tnpr.v7i1.2026.150

Mathias Utip Etim, Jude Efiom Okokon, Grace Emmanuel Essien, Chinyelu Clementina Osigwe, Ugonma Florence Uwaeme 

 

Hepatoprotective Effects of Tetrapleura tetraptera (Schmach & Thonn) Taub, and Vitamin C on Plasma Enzyme Activities and Histopathological Alterations in Cadmium-Induced Wistar Rats
https://doi.org/10.61594/tnpr.v7i1.2026.151

Gregory Elayeche Oko, Micheal Ukpang Ajen, Chibuzor Onyinye Okonkwo, Chidiebere Ogar Ubah, Christopher Abubu Odey, Vo Thi Kim Khuyen. Godwin Eneji Egbung

 

 

 

Patterns and Predictors of Psychoactive Substance Abuse Avoidance Self-Efficacy: Insights from Drug Rehabilitation Centers in Southeast Nigeria

https://doi.org/10.61594/tnpr.v7i1.2026.152

Simeon Ifebuche Ugwu, Chijioke Kenneth Ayogu, Sunday Ogbonna Amu, Victor Ikechukwu Uka, Jeremiah Ukeatabuchi Echa, JohnBosco Chika Chukwuorji

Antiulcer Activity of Herbal Tea Prepared from Unripe Musa paradisiaca Linn. in Rats

https://doi.org/10.61594/tnpr.v7i1.2026.153

Collins Azubuike Onyeto, Marytheresa Akachukwu Onwuka, Virginia Ugo Okeke, Rita Chinecherem Ukwuaba Favour Iluno, Angel Chioma Okafor, Divine Chisom Okafor, Onyeka Stephanie Chiekwe, Kosisochukwu Agatha Ugwa, Amarachi Maureen Okoro. 

 

Acute and Sub-Acute Toxicological Evaluation of the Hydromethanol Seed Extract of Phaseolus lunatus
(Lima Beans) in Wistar Rats

https://doi.org/10.61594/tnpr.v7i1.2026.154

Omorovbiye Cynthia Odeh, Emmar Elohor Okpakpor, Gerald Ikechi Eze, Samuel Frank, Raymond Iduojemu Ozolua

 

Effects of Moringa Oleifera Seed Supplemented Diets on Eimeria tenella Infected Broiler Birds

https://doi.org/10.61594/tnpr.v7i1.2026.155

Zakaria Titilayo Rukayat, Bukar Kaderam Dikwa, Abdullahi Yahaya Umar, Victoria Bakare, Muazu Muhammad

 

Behavioural Evaluation of Pancratium maritimum L. (Amaryllidaceae) Ethanol bulb Extract Reveals Dose-Dependent Antidepressant-Like Effects in Murine Models.

https://doi.org/10.61594/tnpr.v7i1.2026.156

Maryam Ammani Lawal, Gregory Elayeche Oko, Sarah Tanko, Safiya Suleiman Sambo, Danjuma Mallam, Sani Shehu

 

Preliminary Evaluation of the Anti–Inflammatory Activity of the Leaves of Ficus umbellata (VAHL) in Cotton Pellet Induced Granuloma Inflammation Model

https://doi.org/10.61594/tnpr.v7i1.2026.157

Gerald Walter Ugodi, Precious Ogochukwu Didiugwu 

 

 

VOL 6 2025; ISSUE 1

Evaluation of Cytotoxic and Genotoxic Activities of Croton zambesicus Muell Arg. Leaf Extract

https://doi.org/10.61594/tnpr.v6i1.2025.116

Chinyelu Clementina Osigwe, Jude Efiom Okokon, Ukeagbu Wilfred, Ugonma Florence Uwaeme, Imoh Imeh Johnny

 

Bioactivity of Extracts, Fractions, and Compounds of Andrographis paniculata: A Review.

https://doi.org/10.61594/tnpr.v6i1.2025.117

Joshua Inanabor Isibor, Vincent Oghenerobo Imieje, Kennedy Osahon Ogbeide, Osayewemre Erharuyi, Abiodun Falodun

 

 

 

Thesium viride A.W.Hill (Santalaceae): Ethnomedicinal Uses, Chemical Constituents and Pharmacological Activities

https://doi.org/10.61594/tnpr.v6i1.2025.118

Sani Shehu, Yushau Musa Hadi, Uwaisu Iliyasu, Ahmed Danbala Ahmed, Maryam Lawal Ammani   

Antinociceptive Activity of Stem Extract of Telfairia occidentalis Hook in Rodents

https://doi.org/10.61594/tnpr.v6i1.2025.119

Jude Efiom Okokon, Ukeme Essien Andrew, Chinyelu Clementina Osigwe, Uwaeme Ugonma Florence 

 

Acute Antihyperglycaemic Effect of The Combination of Metformin and Ethanol Seed Extract of Moringa oleifera Lam. In Rats

https://doi.org/10.61594/tnpr.v6i1.2025.120

Asma’u Ismail-Junaidu Bashir, Khadijah Abdullahi Isa, Ahmed Ahmed Danbala and Safiya Bala Borodo

 

 

VOL 5 2024; ISSUE 3

Antitrypanosomal activities of ethanol extract of Harungana madagascariensis Lam. ex Poir against Trypanosoma brucei brucei – An in vivo model

https://doi.org/10.61594/tnpr.v5i3.2024.111

Rolayo Toyin Emmanuel, Mercy Erutere Okposio, Mohammed Jatto Salawu, Abubakar Ahmad
Tijjani, Hauwa Muh’d Sabo

 

 

Evaluation of Albumin Denaturation, and Phospholipase A2 (Pla2) Inhibition, and Phytochemical Composition of Methanol Leaf Extract of Psychotria Vogeliana, Benth (Rubiaceae)

https://doi.org/10.61594/tnpr.v5i3.2024.112

Michael Onyegbulam Chukwuma, Ufuoma Shalom Onoabedju, Theodora Chidinma Mba, Chilaka, Samuel Munachi , Benjamin Ezema, Constance Ufomba

 

 

 

The Inhibitory Potentials of the Root Extract and Fractions of Brenania brieyi (De Wild) (Rubiaceae) on Lactate Dehydrogenase, Phospholipase A2, and α- Amylase in Plasmodium falciparum – Infected Persons.

https://doi.org/10.61594/tnpr.v5i3.2024.113

Ifeyinwa Chioma Ezeala , Kingsley Ozioma Omeje, Onyinye Ezeala , Philip Felix Uzor , Obinna William-Fredrick Dim , Adaeze Racheal Anumudu , Ngozi Justina Nwodo   

Evaluation of the Contraceptive Effect of Aqueous Extract of Unripe Fruit of Musa paradisiaca Linn. (Musaceae) in Female Rats.

https://doi.org/10.61594/tnpr.v5i3.2024.114

Collins Azubuike Onyeto, Chiamaka Linda Ekowo 

 

Antidiarheal Activity of Methanol Seed Extract of Cola Acuminata Schott & Endl (Malvaceae) In Mice

https://doi.org/10.61594/tnpr.v5i3.2024.115

Abdulhamid Musa Inuwa, Ibrahim Mu’azzamu Aliyu , Maryam Bala Muhammad,
Zakiyyah Yakubu Yahaya Ibrahim

 

 

VOL 5 2024; ISSUE 2

Evaluation of Dacryodes edulis Cream Formulations Against Some Causative Agents of Skin Infection

Babalola Sunday Aponjolosun, Tolulope Omolola Ajala and Taiye Remi Fasola

 

 

The Nexus Between African Religious Belief and African Traditional Medicine

Josephine Ngozi Akah

 

 

 

Anti-Diabetic Activity of Ethanol Stem Bark Extract of Dacryodes Klaineana (Pierre) H. J. Lam (Burseraceae) On Alloxan Induced Diabetic Rats.

Patrick Ebele Obi, Kelvin Onyedikachi Ebuoh-Ike, Chukwunonso Ebere Obi  

Phytochemical and Larvicidal Evaluation of Vernonia Glaberrima Welw. Ex O. Hoffm. (Asteraceae) Leaves on Aedes Mosquito Larvae

Sabastine Obinna Onugwu, Adaeze Linda Onugwu, Christopher Obodike Ezugwu 

 

Evaluation of the Anti-IAnti-arthritic and Antioxidant Potentials of Leaf Extract of Atrocarpus heterophyllus Lam

Victoria Nonyelum Olli Nneoma Ngozi Okpalanma, Ernest C. Orji, Jude Nnaemeka Okoyeh

Pharmacognostic Properties and Mosquito Repellent Activity of the Leaf Extract of Vernonia glaberrima (Asteraceae) Welw. Ex O. Hoffm against Aedes aegypti Mosquito

Sabastine Obinna Onugwu, Linda Adaeze Onugwu, Onyinye Ugwu

 

 

 

VOL 5 2024; ISSUE 1

Basics and Fundamentals of Natural Product Research

Michael Onyegbulam Chukwuma, Theodora Chidinma Mba, Ikenna Chikeokwu2

 

 

Acute and Sub-Chronic Toxicity Profile of Aqueous Fruit Extract of Spondias purpurea Linn (Anacardiaceae): In Wistar Rats

Ibrahim Abdullahi Abubakar, Helen Kwanashie Ochuko, Sherifat Anafi Bola , Mohammed Mahdi Abubakar, Jonah Omonofa Oluwaiye

 

 

 

Quality Assessment of Some Herbal Aphrodisiac Instant Coffee Premix Products Marketed in Kaduna, Nigeria

Rukayyat Bukola Oloyede, Abdulkadir Bashir, Suzie Kuzasai Luka, Musa Abdullahi Garba, Abduljalal Danbaba, Salisu Awwalu, Asmau A. Kassim, Abdlfatai Adetunji Jimoh  

Anti-Inflammatory and Antipyretic Activity of Methanol Leaf Extract of Phoenix reclinata, Jacq (Aracaceae)

Paul Chinwuba, Peter Achunike. Akah, Chukwuemeka Sylvester Nworu 

 

Evaluation of the Anti-Inflammatory and Antioxidant, Activities of Parinari curatellifolia Planch. Ex Benth. (Chrysobalanaceae) Methanol Stem Bark Extract

Theodora Chidinma2, Michael Onyegbulam Chukwuma1*, Estella Uchenna Odoh1, Ikenna Chikeokwu2